Insulin degludec: Lower day-to-day and within-day variability in pharmacodynamic response compared with insulin glargine 300 U/mL in type 1 diabetes
Author:
Affiliation:
1. Profil; Neuss Germany
2. Novo Nordisk A/S; Søborg Denmark
Funder
Novo Nordisk A/S
Publisher
Wiley
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/dom.12938/fullpdf
Reference19 articles.
1. Old and new basal insulin formulations: understanding pharmacodynamics is still relevant in clinical practice;Rossetti;Diabetes Obes Metab,2014
2. Impact of the mode of protraction of basal insulin therapies on their pharmacokinetic and pharmacodynamic properties and resulting clinical outcomes;Heise;Diabetes Obes Metab,2017
3. A review of the pharmacological properties of insulin degludec and their clinical relevance;Haahr;Clin Pharmacokinet,2014
4. Lower within-subject variability of insulin detemir in comparison to NPH insulin and insulin glargine in people with type 1 diabetes;Heise;Diabetes,2004
5. Insulin degludec: four times lower pharmacodynamic variability than insulin glargine under steady-state conditions in type 1 diabetes;Heise;Diabetes Obes Metab,2012
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