The γ-Secretase Blocker DAPT Reduces the Permeability of the Blood-Brain Barrier by Decreasing the Ubiquitination and Degradation of Occludin During Permanent Brain Ischemia-Reference-Cited by-同舟云学术

The γ-Secretase Blocker DAPT Reduces the Permeability of the Blood-Brain Barrier by Decreasing the Ubiquitination and Degradation of Occludin During Permanent Brain Ischemia

Published:2012-11-22 Issue:1 Volume:19 Page:53-60
ISSN:1755-5930
Container-title:CNS Neuroscience & Therapeutics
language:en
Short-container-title:CNS Neurosci Ther

Author:

Zhang Gen-Sheng,Tian Yun¹,Huang Ji-Yun¹,Tao Rong-Rong¹,Liao Mei-Hua¹,Lu Ying-Mei²,Ye Wei-Feng,Wang Rui¹,Fukunaga Kohji³,Lou Yi-Jia¹,Han Feng¹

Affiliation:

1. Institute of Pharmacology; Toxicology and Biochemical Pharmaceutics; Zhejiang University; Hangzhou; China

2. Department of Neurobiology; Key Laboratory of Medical Neurobiology of Ministry of Health of China; Zhejiang University School of Medicine; Hangzhou; China

3. Department of Pharmacology; Graduate School of Pharmaceutical Sciences; Tohoku University; Sendai; Japan

Publisher

Wiley

Subject

Pharmacology (medical),Physiology (medical),Psychiatry and Mental health,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cns.12032/fullpdf

Reference39 articles.

1. Microsphere embolism-induced endothelial nitric oxide synthase expression mediates disruption of the blood-brain barrier in rat brain;Han;J Neurochem,2006

2. AQP4 knockout aggravates ischemia/reperfusion injury in mice;Zeng;CNS Neurosci Ther,2012

3. Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective;Cheng;Nat Med,2003

4. Targeting nitrosative stress for neurovascular protection: new implications in brain diseases;Tao;Curr Drug Targets,2012

5. The proteome of mouse brain microvessel membranes and basal lamina;Chun;J Cereb Blood Flow Metab,2011

Cited by 44 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. An easy-to-perform method for microvessel isolation and primary brain endothelial cell culture to study Alzheimer's disease;Heliyon;2024-06

2. The Basic Requirement of Tight Junction Proteins in Blood-Brain Barrier Function and Their Role in Pathologies;International Journal of Molecular Sciences;2024-05-21

3. Endothelial lincRNA-p21 alleviates cerebral ischemia/reperfusion injury by maintaining blood-brain barrier integrity;Journal of Cerebral Blood Flow & Metabolism;2024-04-25

4. A Novel Perspective on PCSK9 in Alzheimer’s Disease: A Focus on Amyloid Beta;Current Medicinal Chemistry;2024-02-16

5. Blood-brain barrier dysfunction and Alzheimer’s disease: associations, pathogenic mechanisms, and therapeutic potential;Frontiers in Aging Neuroscience;2023-11-13