Platelet binding and activity of a factor VIIa variant with enhanced tissue factor independent activity
Author:
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1538-7836.2011.04223.x/fullpdf
Reference31 articles.
1. Mechanism of factor VIIa-dependent coagulation in hemophilia blood;Butenas;Blood,2002
2. Platelet activity of high-dose factor VIIa is independent of tissue factor;Monroe;Br J Haematol,1997
3. Tissue factor-independent effects of recombinant factor VIIa on hemostasis;Weeterings;Semin Hematol,2008
4. Rational design of coagulation factor VIIa variants with substantially increased intrinsic activity;Persson;Proc Natl Acad Sci USA,2001
5. A variant of recombinant factor VIIa with enhanced procoagulant and antifibrinolytic activities in an in vitro model of hemophilia;Allen;Arterioscler Thromb Vasc Biol,2007
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1. Enhanced potency of recombinant factor VIIa with increased affinity to activated platelets;Journal of Thrombosis and Haemostasis;2019-10-14
2. Mitigation of T-cell dependent immunogenicity by reengineering factor VIIa analogue;Blood Advances;2019-09-10
3. Eptacog beta: a novel recombinant human factor VIIa for the treatment of hemophilia A and B with inhibitors;Expert Review of Hematology;2019-01-02
4. Targeting platelet EPCR for better therapeutic factor VIIa activity;Journal of Thrombosis and Haemostasis;2018-08-03
5. Human platelets express endothelial protein C receptor, which can be utilized to enhance localization of factor VIIa activity;Journal of Thrombosis and Haemostasis;2018-06-27
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