QM/MM modelling of ketosteroid isomerase reactivity indicates that active site closure is integral to catalysis
Author:
Affiliation:
1. Centre for Computational Chemistry; School of Chemistry; University of Bristol; Bristol; UK
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/febs.12158/fullpdf
Reference70 articles.
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3. Energetics of 3-oxo-Δ5-steroid isomerase: source of the catalytic power of the enzyme;Hawkinson;Biochemistry,1991
4. The principle of nonperfect synchronization;Bernasconi;Adv Phys Org Chem,1992
5. The principle of nonperfect synchronization - more than a qualitative concept;Bernasconi;Acc Chem Res,1992
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