Evolution of dynamical networks enhances catalysis in a designer enzyme-Reference-Cited by-同舟云学术

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Evolution of dynamical networks enhances catalysis in a designer enzyme

Published:2021-08-19 Issue:10 Volume:13 Page:1017-1022
ISSN:1755-4330
Container-title:Nature Chemistry
language:en
Short-container-title:Nat. Chem.

Author:

Bunzel H. Adrian,Anderson J. L. Ross,Hilvert Donald^ORCID,Arcus Vickery L.,van der Kamp Marc W.^ORCID,Mulholland Adrian J.^ORCID

Funder

RCUK | Engineering and Physical Sciences Research Council

RCUK | Biotechnology and Biological Sciences Research Council

Marsden Fund of New Zealand

Swiss National Science Foundation

Royal Marsden NHS Foundation Trust

Publisher

Springer Science and Business Media LLC

Subject

General Chemical Engineering,General Chemistry

Link

https://www.nature.com/articles/s41557-021-00763-6.pdf

Reference54 articles.

1. Arnold, F. H. Innovation by evolution: bringing new chemistry to life (Nobel Lecture). Angew. Chem. Int. Ed. 58, 14420–14426 (2019).

2. Bornscheuer, U. T. et al. Engineering the third wave of biocatalysis. Nature 485, 185–194 (2012).

3. Tournier, V. et al. An engineered PET depolymerase to break down and recycle plastic bottles. Nature 580, 216–219 (2020).

4. Kries, H., Blomberg, R. & Hilvert, D. De novo enzymes by computational design. Curr. Opin. Chem. Biol. 17, 221–228 (2013).

5. Kiss, G., Çelebi-Ölçüm, N., Moretti, R., Baker, D. & Houk, K. N. Computational enzyme design. Angew. Chem. Int. Ed. 52, 5700–5725 (2013).

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