Multiscale Simulations Identify Origins of Differential Carbapenem Hydrolysis by the OXA-48 β-Lactamase-Reference-Cited by-同舟云学术

Multiscale Simulations Identify Origins of Differential Carbapenem Hydrolysis by the OXA-48 β-Lactamase

Published:2022-04-04 Issue:8 Volume:12 Page:4534-4544
ISSN:2155-5435
Container-title:ACS Catalysis
language:en
Short-container-title:ACS Catal.

Author:

Hirvonen Viivi H. A.¹²^ORCID,Weizmann Tal Moshe¹,Mulholland Adrian J.²^ORCID,Spencer James³^ORCID,van der Kamp Marc W.¹²^ORCID

Affiliation:

1. School of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, U.K.

2. Centre for Computational Chemistry, School of Chemistry, University of Bristol, Cantock’s Close, Bristol BS8 1TS, U.K.

3. School of Cellular and Molecular Medicine, University of Bristol, University Walk, Bristol BS8 1TD, U.K.

Funder

Engineering and Physical Sciences Research Council

Medical Research Council

Biotechnology and Biological Sciences Research Council

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscatal.1c05694

Reference67 articles.

1. Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 β-Lactamase

2. Antibiotic Resistance. World Health Organization, July 31, 2020. https://www.who.int/news-room/fact-sheets/detail/antibiotic-resistance (accessed 2021-01-19).

3. Antibiotic resistance is ancient

4. Use and Prescription of Antibiotics in Primary Health Care Settings in China

5. Origins and Evolution of Antibiotic Resistance

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