Protein phosphatase 5 mediates corticosteroid insensitivity in airway smooth muscle in patients with severe asthma
Author:
Affiliation:
1. Department of Infection, Immunity and Inflammation; University of Leicester; Leicester UK
2. Department of Pharmaceutical Sciences; Jefferson School of Pharmacy; Thomas Jefferson University; Philadelphia PA USA
Funder
ERDF
National Institute for Health Research
National Institutes of Health
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/all.13003/fullpdf
Reference44 articles.
1. The investigation of severe asthma to define phenotypes;Gibeon;Clin Exp Allergy,2012
2. Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease;Barnes;J Allergy Clin Immunol,2013
3. Pathogenesis of severe asthma;Poon;Clin Exp Allergy,2012
4. Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients;Matthews;J Allergy Clin Immunol,2004
5. Restoration of corticosteroid sensitivity by p38 mitogen activated protein kinase inhibition in peripheral blood mononuclear cells from severe asthma;Mercado;PLoS One,2012
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