In vitroEnhancement of Antitumor Activity of a Water-soluble Duocarmycin Derivative, KW-2189, by Caffeine-mediated DNA-repair Inhibition in Human Lung Cancer Cells-Reference-Cited by-同舟云学术

In vitroEnhancement of Antitumor Activity of a Water-soluble Duocarmycin Derivative, KW-2189, by Caffeine-mediated DNA-repair Inhibition in Human Lung Cancer Cells

Published:1997-11 Issue:11 Volume:88 Page:1033-1037
ISSN:0910-5050
Container-title:Japanese Journal of Cancer Research
language:en
Short-container-title:

Author:

Ogasawara Hayato,Nishio Kazuto,Ishida Tomoyuki,Arioka Hitoshi,Fukuoka Kazuya,Saijo Nagahiro

Publisher

Wiley

Subject

Cancer Research,Oncology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1349-7006.1997.tb00326.x/fullpdf

Reference15 articles.

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2. Characteristics of antitumor activity of KW-2189, a novel water-soluble derivative of duocarmycin, against murine and human tumors;Kobayashi;Cancer Res.,1994

3. A novel antitumor antibiotic, KW-2189 is activated by carboxyl esterase and induces DNA strand breaks in human small cell lung cancer cells;Ogasawara;Jpn. J. Cancer Res.,1994

4. Intracellular carboxyl esterase activity is a determinant of cellular sensitivity to the antineoplastic agent KW-2189 in cell lines resistant to cisplatin and CPT-11;Ogasawara;Jpn. J. Cancer Res.,1995

5. Synthesis and preliminary evaluation of agents incorporating the pharmacophore of the duocarmycin/pyrindamycin alkylation subunit: identification of the CC-1065/duocarmycin common pharmacophore;Boger;J. Org. Chem.,1990

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