1. Clinical Pharmacology Laboratory; Henan Province People's Hospital; Zhengzhou University People's Hospital; 7 Weiwu Road Jinshui District Zhengzhou 450003 China
2. Key Laboratory of Structure-Based Drug Design and Discovery; Ministry of Education; Shenyang Pharmaceutical University; 103 Wenhua Road Shenhe District Shenyang 110016 China
3. Department of Pharmacology; Shenyang Pharmaceutical University; 103 Wenhua Road Shenhe District Shenyang 110016 China
4. Division of Hematology/Oncology; Department of Medicine; Beth Israel Deaconess Medical Center and Harvard Medical School; Boston MA 02215 USA