An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site-Reference-Cited by-同舟云学术

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An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site

Published:2012-07-20 Issue:11 Volume:29 Page:2943-2971
ISSN:0724-8741
Container-title:Pharmaceutical Research
language:en
Short-container-title:Pharm Res

Author:

Lu Yan,Chen Jianjun,Xiao Min,Li Wei,Miller Duane D.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology

Link

http://link.springer.com/content/pdf/10.1007/s11095-012-0828-z.pdf

Reference160 articles.

1. Pryor DE, O'Brate A, Bilcer G, Diaz JF, Wang Y, Kabaki M, et al. The microtubule stabilizing agent laulimalide does not bind in the taxoid site, kills cells resistant to paclitaxel and epothilones, and may not require its epoxide moiety for activity. Biochemistry. 2002;41:9109–15.

2. Gigant B, Wang C, Ravelli RB, Roussi F, Steinmetz MO, Curmi PA, et al. Structural basis for the regulation of tubulin by vinblastine. Nature. 2005;435:519–22.

3. Ravelli RB, Gigant B, Curmi PA, Jourdain I, Lachkar S, Sobel A, et al. Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain. Nature. 2004;428:198–202.

4. Seveand P, Dumontet C. Is class III beta-tubulin a predictive factor in patients receiving tubulin-binding agents? The Lancet Oncology. 2008;9:168–75.

5. Stengel C, Newman SP, Leese MP, Potter BV, Reed MJ, Purohit A. Class III beta-tubulin expression and in vitro resistance to microtubule targeting agents. Br J Cancer. 2010;102:316–24.

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