Transcription factors CEP-1/p53 and CEH-23 collaborate with AAK-2/AMPK to modulate longevity in Caenorhabditis elegans .

Author:

Chang Hsin-Wen1,Pisano Steve1,Chaturbedi Amaresh1,Chen Jennifer1,Gordon Sarah1,Baruah Aiswarya1,Lee Siu Sylvia1

Affiliation:

1. Department of Molecular Biology and Genetics; Cornell University; Ithaca NY 14853 USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Cell Biology,Aging

Reference48 articles.

1. A regulatory cascade of three homeobox genes, ceh-10, ttx-3 and ceh-23, controls cell fate specification of a defined interneuron class in C. elegans;Altun-Gultekin;Development,2001

2. The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans;Apfeld;Genes Dev.,2004

3. CEP-1, the Caenorhabditis elegans p53 Homolog, mediates opposing longevity outcomes in mitochondrial electron transport chain mutants;Baruah;PLoS Genet.,2014

4. AMPK at the nexus of energetics and aging;Burkewitz;Cell Metab.,2014

5. Neuronal CRTC-1 governs systemic mitochondrial metabolism and lifespan via a catecholamine signal;Burkewitz;Cell,2015

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