CEP-1, the Caenorhabditis elegans p53 Homolog, Mediates Opposing Longevity Outcomes in Mitochondrial Electron Transport Chain Mutants

Author:

Baruah Aiswarya,Chang Hsinwen,Hall Mathew,Yuan Jie,Gordon Sarah,Johnson Erik,Shtessel Ludmila L.,Yee Callista,Hekimi Siegfried,Derry W. Brent,Lee Siu Sylvia

Publisher

Public Library of Science (PLoS)

Subject

Cancer Research,Genetics (clinical),Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics

Reference43 articles.

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2. Extension of Drosophilla lifespan by RNAi of the mitochondrial respiratory chin;JM Copeland;Curr Biol,2009

3. Early mitochondrial dysfunction in long-lived Mclk1+/− mice;J Lapointe;J Biol Chem,2008

4. Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans;SL Rea;PLoS Biol,2007

5. Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans;JM Van Raamsdonk;PLoS Genet,2009

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