Repeated administration of IL-31 upregulates IL-31 receptor A (IL-31RA) in dorsal root ganglia and causes severe itch-associated scratching behaviour in mice
Author:
Affiliation:
1. Department of Pharmacology; International University of Health and Welfare; Ohtawara Tochigi Japan
2. Department of Molecular Immunology; Institute of DNA Medicine; Jikei University Minato-ku; Tokyo Japan
Publisher
Wiley
Subject
Dermatology,Molecular Biology,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/exd.12587/fullpdf
Reference20 articles.
1. Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice
2. Expression of IL-31 gene transcripts in NC/Nga mice with atopic dermatitis
3. Involvement of IL-31 on scratching behavior in NC/Nga mice with atopic-like dermatitis
4. Development of atopic dermatitis-like skin lesion with IgE hyperproduction in NC/Nga mice
5. Characterization of itch-associated responses of NC mice with mite-induced chronic dermatitis
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