Inhibition of complement component C5 prevents clotting in an ex vivo model of xenogeneic activation of coagulation

Author:

Rataj Dennis1,Werwitzke Sonja1,Haarmeijer Birgitt1,Winkler Michael2,Ramackers Wolf2,Petersen Björn3,Niemann Heiner3,Wünsch Annegret4,Bähr Andrea4,Klymiuk Nikolai4,Wolf Eckhard4,Abicht Jan-Michael5,Ayares David6,Tiede Andreas1

Affiliation:

1. Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation; Hannover Medical School; Hannover Germany

2. Department for General, Visceral and Transplantation Surgery; Hannover Medical School; Hannover Germany

3. Institute of Farm Animal Genetics; Friedrich-Loeffler-Institute; Neustadt Germany

4. Molecular Animal Breeding and Biotechnology; Gene Center and Department of Veterinary Sciences; Ludwig Maximilian University of Munich; Munich Germany

5. Department of Anesthesiology; Ludwig Maximilian University of Munich; Munich Germany

6. Revivicor, Inc.; Blacksburg VA USA

Funder

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Transplantation,Immunology

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