Expression of human thrombomodulin on porcine endothelial cells can reduce platelet aggregation but did not reduce activation of complement or endothelium – an experimental study-Reference-Cited by-同舟云学术

Expression of human thrombomodulin on porcine endothelial cells can reduce platelet aggregation but did not reduce activation of complement or endothelium – an experimental study

Published:2020-02-09 Issue:4 Volume:33 Page:437-449
ISSN:0934-0874
Container-title:Transplant International
language:en
Short-container-title:Transpl Int

Author:

Ramackers Wolf¹^ORCID,Rataj Dennis²,Werwitzke Sonja²,Bergmann Sabine¹,Winkler Michael¹,Wünsch Annegret³,Bähr Andrea³,Wolf Eckard³,Klymiuk Nikolai³,Ayares David⁴,Tiede Andreas²

Affiliation:

1. Department for General, Visceral and Transplantation Surgery Hannover Medical School Hannover Germany

2. Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation Hannover Medical School Hannover Germany

3. Molecular Animal Breeding and Biotechnology Gene Center and Department of Veterinary Sciences LMU Munich Munich Germany

4. Revivicor, Inc. Blacksburg VA USA

Funder

Deutsche Forschungsgemeinschaft

Publisher

Frontiers Media SA

Subject

Transplantation

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/tri.13573

Reference34 articles.

1. Spectrum of the Early Xenograft Response: From Hyperacute Rejection to Delayed Xenograft Injury

2. Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs

3. TRANSGENIC PIGS EXPRESSING HUMAN CD59 AND DECAY-ACCELERATING FACTOR PRODUCE AN INTRINSIC BARRIER TO COMPLEMENT-MEDIATED DAMAGE1

4. Human CD55 Expression Blocks Hyperacute Rejection and Restricts Complement Activation in Gal Knockout Cardiac Xenografts

5. ACUTE VASCULAR REJECTION OF XENOGRAFTS: ROLES OF NATURAL AND ELICITED XENOREACTIVE ANTIBODIES IN ACTIVATION OF VASCULAR ENDOTHELIAL CELLS AND INDUCTION OF PROCOAGULANT ACTIVITY

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1. Genetically modified immunomodulatory cell-based biomaterials in tissue regeneration and engineering;Cytokine & Growth Factor Reviews;2022-08

2. hEPCR.hTBM.hCD47.hHO‐1 with donor clodronate and DDAVP treatment improves perfusion and function of GalTKO.hCD46 porcine livers perfused with human blood;Xenotransplantation;2022-02-15

3. PI3K Isoform Signalling in Platelets;Current Topics in Microbiology and Immunology;2022

4. Differences in platelet aggregometers to study platelet function and coagulation dysregulation in xenotransplantation;Xenotransplantation;2020-09-18