Characterization of equine cytochrome P450: role of CYP3A in the metabolism of diazepam-Reference-Cited by-同舟云学术

Characterization of equine cytochrome P450: role of CYP3A in the metabolism of diazepam

Published:2016-03-11 Issue:5 Volume:39 Page:478-487
ISSN:0140-7783
Container-title:Journal of Veterinary Pharmacology and Therapeutics
language:en
Short-container-title:J. vet. Pharmacol. Therap.

Author:

Nakayama S. M. M.¹,Ikenaka Y.¹²,Hayami A.¹,Mizukawa H.³,Darwish W. S.¹⁴,Watanabe K. P.¹,Kawai Y. K.¹⁵,Ishizuka M.¹

Affiliation:

1. Laboratory of Toxicology; Department of Environmental Veterinary Sciences; Graduate School of Veterinary Medicine; Hokkaido University; Kita-ku Sapporo Japan

2. Water Research Group; Unit for Environmental Sciences and Management; North-West University; Potchefstroom South Africa

3. Department of Environmental Veterinary Sciences; Graduate School of Veterinary Medicine; Hokkaido University; Kita-ku Sapporo Japan

4. Food Control Department; Faculty of Veterinary Medicine; Zagazig University; Zagazig Egypt

5. Diagnostic Center for Animal Health and Food Safety; Obihiro University of Agriculture and Veterinary Medicine; Obihiro Japan

Funder

Ministry of Education, Culture, Sports, Science, and Technology

JSPS Core to Core Program

Bilateral Joint Research Project

Mitsui and Company

Publisher

Wiley

Subject

General Veterinary,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/am-pdf/10.1111%2Fjvp.12303

Reference34 articles.

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2. Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms;Andersson;British Journal of Clinical Pharmacology,1994

3. In vitro comparison of cytochrome P450-mediated metabolic activities in human, dog, cat, and horse;Chauret;Drug Metabolism and Disposition,1997

4. Substrate selectivity of drug-metabolizing cytochrome P450s predicted from crystal structures and in silico modeling;Dong;Drug Metabolism Reviews,2002

5. MUSCLE: multiple sequence alignment with high accuracy and high throughput;Edgar;Nucleic Acids Research,2004

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