Substrate selectivity of drug-metabolizing cytochrome P450s predicted from crystal structures andin silicomodeling
Author:
Publisher
Informa UK Limited
Subject
Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics
Link
http://www.tandfonline.com/doi/pdf/10.3109/03602532.2011.645580
Reference85 articles.
1. NON-MICHAELIS-MENTEN KINETICS IN CYTOCHROME P450-CATALYZED REACTIONS
2. Allosteric P450 mechanisms: multiple binding sites, multiple conformers or both?
3. Novel Approach To Predicting P450-Mediated Drug Metabolism: Development of a Combined Protein and Pharmacophore Model for CYP2D6
4. Development of a Combined Protein and Pharmacophore Model for Cytochrome P450 2C9
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