Evaluation and use of an anti‐cynomolgus monkey CD79b surrogate antibody–drug conjugate to enable clinical development of polatuzumab vedotin-Reference-Cited by-同舟云学术

Evaluation and use of an anti‐cynomolgus monkey CD79b surrogate antibody–drug conjugate to enable clinical development of polatuzumab vedotin

Published:2019-08-24 Issue:19 Volume:176 Page:3805-3818
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:Br J Pharmacol

Author:

Li Dongwei¹^ORCID,Lee Donna²,Dere Randall C.³,Zheng Bing⁴,Yu Shang‐Fan⁴,Fuh Franklin K.⁵,Kozak Katherine R.⁶,Chung Shan³,Bumbaca Yadav Daniela¹,Nazzal Denise³,Danilenko Dimitry²,Go Mary Ann T.⁴,Williams Marna⁷,Polson Andrew G.⁴,Poon Kirsten Achilles⁸,Prabhu Saileta¹

Affiliation:

1. Department of Pharmacokinetic and Pharmacodynamic SciencesGenentech, Inc. South San Francisco CA USA

2. Department of Safety AssessmentGenentech, Inc. South San Francisco CA USA

3. Department of BioAnalytical SciencesGenentech, Inc. South San Francisco CA USA

4. Department of Translational OncologyGenentech, Inc. South San Francisco CA USA

5. Department of OMNI‐Biomarker DevelopmentGenentech, Inc. South San Francisco CA USA

6. Department of Biochemical and Cellular PharmacologyGenentech, Inc. South San Francisco CA USA

7. Department of Translational MedicineMedImmune Gaithersburg MD USA

8. Department of Pharmacology and ToxicologyUltragenyx Pharmaceutical, Inc. Novato CA USA

Funder

Genentech

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bph.14784

Reference35 articles.

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5. Cathepsin B Is Dispensable for Cellular Processing of Cathepsin B-Cleavable Antibody–Drug Conjugates

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