Clinical pharmacology strategies to accelerate the development of polatuzumab vedotin and summary of key findings

Author:

Liao Michael Z.,Lu Dan,Lu Tong,Gibiansky Leonid,Deng Rong,Samineni Divya,Dere Randall,Lin Andy,Hirata Jamie,Shen Ben-Quan,Zhang Donglu,Li Dongwei,Li Chunze,Miles Dale

Funder

F. Hoffmann-La Roche

F. Hoffmann-La Roche Ltd

Publisher

Elsevier BV

Reference49 articles.

1. Genentech Inc. POLIVY® [polatuzumab vedotin-piiq] Prescribing Information. Available at: https://www.gene.com/download/pdf/polivy_prescribing.pdf (2023). Accessed May 2023.

2. Polatuzumab vedotin in relapsed or refractory diffuse large B-cell lymphoma;Sehn;J. Clin. Oncol.,2020

3. Therapeutic potential of an anti-CD79b antibody-drug conjugate, anti-CD79b-vc-MMAE, for the treatment of non-Hodgkin lymphoma;Dornan;Blood,2009

4. Development of potent monoclonal antibody auristatin conjugates for cancer therapy;Doronina;Nat. Biotechnol.,2003

5. Anti-CD22 and anti-CD79b antibody-drug conjugates preferentially target proliferating B cells;Fuh;Br. J. Pharmacol.,2017

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