Structure-activity relationships of arodyn, a novel acetylated kappa opioid receptor antagonist*,+
Author:
Publisher
Wiley
Subject
Endocrinology,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1399-3011.2005.00216.x/fullpdf
Reference40 articles.
1. Structure-Activity Relationships of Arodyn, a Novel Dynorphin A-(1–11) Analogue
2. An open-label study of a functional opioid κ antagonist in the treatment of opioid dependence
3. Antidepressant-Like Effects of κ-Opioid Receptor Antagonists in the Forced Swim Test in Rats
4. Binaltorphimine and nor-binaltorphimine, potent and selective k-opioid receptor antagonists
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1. A Bicyclic Analog of the Linear Peptide Arodyn Is a Potent and Selective Kappa Opioid Receptor Antagonist;Molecules;2024-06-29
2. Quantification of kappa opioid receptor ligand potency, efficacy and desensitization using a real-time membrane potential assay;Biomedicine & Pharmacotherapy;2021-11
3. Analogs of the κ opioid receptor antagonist arodyn cyclized by ring-closing metathesis retain κ opioid receptor affinity, selectivity and κ opioid receptor antagonism;Medicinal Chemistry Research;2021-06-17
4. Conformational Constraint between Aromatic Residue Side Chains in the “Message” Sequence of the Peptide Arodyn Using Ring Closing Metathesis Results in a Potent and Selective Kappa Opioid Receptor Antagonist;Journal of Medicinal Chemistry;2021-03-10
5. Design, synthesis, and opioid activity of arodyn analogs cyclized by ring-closing metathesis involving Tyr(allyl);Bioorganic & Medicinal Chemistry;2018-03
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