Clinical significance of CYP2C19 polymorphisms on the metabolism and pharmacokinetics of 11β-hydroxysteroid dehydrogenase type-1 inhibitor BMS-823778
Author:
Affiliation:
1. Pharmaceutical Candidate Optimization; Bristol-Myers Squibb; Princeton NJ USA
2. Regulatory Documentation Strategy; Bristol-Myers Squibb; Princeton NJ USA
3. Genentech; South San Francisco CA USA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.13421/fullpdf
Reference34 articles.
1. Glucocorticoids, metabolism and metabolic diseases;Vegiopoulos;Mol Cell Endocrinol,2007
2. Cortisol metabolism and the role of 11beta-hydroxysteroid dehydrogenase;Tomlinson;Best Pract Res Clin Endocrinol Metab,2001
3. Obesity and cortisol;Bjorntorp;Nutrition,2000
4. Overexpression of 11beta-hydroxysteroid dehydrogenase-1 in adipose tissue is associated with acquired obesity and features of insulin resistance: studies in young adult monozygotic twins;Kannisto;J Clin Endocrinol Metab,2004
5. Local and systemic impact of transcriptional up-regulation of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue in human obesity;Wake;J Clin Endocrinol Metab,2003
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