The Regulatory Framework Across International Jurisdictions for Risks Associated with Consumption of Botanical Food Supplements

Author:

Low Teng Yong12ORCID,Wong Kwok Onn2,Yap Adelene L. L.2,De Haan Laura H. J.1,Rietjens Ivonne M. C. M.1

Affiliation:

1. Div. of Toxicology; Wageningen Univ.; Stippeneng 4 6708 WE Wageningen The Netherlands

2. Regulatory Programs Dept., Regulatory Administration Group; Agri-Food & Veterinary Authority of Singapore; 52 Jurong Gateway Road Singapore 608550 Singapore

Funder

Agri-Food and Veterinary Authority

Publisher

Wiley

Subject

Food Science

Reference118 articles.

1. Risk assessment of plant food supplements and other herbal products containing aristolochic acids using the margin of exposure (MOE) approach;Abdullah;Food Addit Contam Part A Chem Anal Contr Expo Risk Assess,2016

2. Advisory Committee on Novel Foods and Processes (ACNFP) 2002 Guidelines on the use of human studies in the pre-market safety assessment of novel foods https://acnfp.food.gov.uk/committee/acnfp/acnfppapers/inforelatass/guidetastehuman/guidlinespre-market

3. Agence Française de Sécurité Sanitaire des Aliments (Afssa) 2003 Framework for the evaluation of the safety, the effect and the claims of foodstuff, made from plants, for the human diet https://www.anses.fr/en/system/files/NUT-Ra-PlantesEN.pdf

4. Identification of nevadensin as an important herb-based constituent inhibiting estragole bioactivation and physiology-based biokinetic modeling of its possible in vivo effect;Alhusainy;Toxicol Appl Pharmacol,2010

5. Matrix modulation of the bioactivation of estragole by constituents of different alkenylbenzene-containing herbs and spices and physiologically based biokinetic modeling of possible in vivo effects;Alhusainy;Toxicol Sci,2012

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