Identification of nevadensin as an important herb-based constituent inhibiting estragole bioactivation and physiology-based biokinetic modeling of its possible in vivo effect

Author:

Alhusainy W.,Paini A.,Punt A.,Louisse J.,Spenkelink A.,Vervoort J.,Delatour T.,Scholz G.,Schilter B.,Adams T.,van Bladeren P.J.,Rietjens I.M.C.M.

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference62 articles.

1. Common food additives are potent inhibitors of human liver 17α-ethinyloestradiol and dopamine sulphotransferases;Bamforth;Biochem. Pharmacol.,1993

2. Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1′-sulfooxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1′-hydroxysafrole in mouse liver;Boberg;Cancer Res.,1983

3. The metabolism of the naturally occurring hepatocarcinogen safrole to 1′-hydroxysafrole and the electrophilic reactivity of 1′-acetoxysafrole;Borchert;Cancer Res.,1973

4. Flavonoid-mediated inhibition of intestinal ABC transporters may affect the oral bioavailability of drugs, food-borne toxic compounds and bioactive ingredients;Brand;Biomedicine and Pharmacotherapy,2006

5. Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells;Cavin;Food Chem. Toxicol.,2001

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