Design, Synthesis and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel DPP-4 Inhibitors-Reference-Cited by-同舟云学术

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Design, Synthesis and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel DPP-4 Inhibitors

Published:2015-04-12 Issue:4 Volume:86 Page:849-856
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Li Qing¹,Zhou Muxing¹,Han Li¹,Cao Qing¹,Wang Xinning¹,Zhao LeiLei¹,Zhou Jinpei²,Zhang Huibin¹³

Affiliation:

1. Center of Drug Discovery; China Pharmaceutical University; Nanjing 210009 China

2. Department of Medicinal Chemistry; China Pharmaceutical University; 24 Tongjia Xiang Nanjing 210009 China

3. Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease; China Pharmaceutical University; Nanjing 210009 China

Funder

China National Key Hi-Tech Innovation Project for the R&D of Novel Drugs

Natural Science Foundation of Jiangsu Province

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12560/fullpdf

Reference29 articles.

1. The worldwide epidemiology of type 2 diabetes mellitus-present and future perspectives;Chen;Nat Rev Endocrinol,2012

2. Diabetes in China: mapping the road ahead;The Lancet. Diabetes & Endocrinology;Lancet Diabetes Endocrinol,2014

3. Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future;Kahn;Lancet,2014

4. Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV;Lambeir;Crit Rev Clin Lab Sci,2003

5. Molecular mechanisms of incretin hormone secretion;Ezcurra;Curr Opin Pharmacol,2013

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1. Novel imidazo[2,1-b]thiazoles and imidazo[1,2-a]pyridines tethered with indolinone motif as VEGFR-2 inhibitors and apoptotic inducers: Design, synthesis and biological evaluations;Bioorganic Chemistry;2024-10

2. Multicomponent Cross-Dehydrogenative Coupling of Imidazo[1,2-a]pyridine: Access to Abnormal Mannich and Mannich-Type Reaction;The Journal of Organic Chemistry;2024-07-17

3. Recent advances and structure-activity relationship studies of DPP-4 inhibitors as anti-diabetic agents;Bioorganic Chemistry;2024-05

4. Efficient synthesis of glycosylated imidazo[1,2-a]pyridines via solvent catalysed Groebke-Blackburn-Bienayme reaction;Carbohydrate Research;2023-12

5. Synthesis of 2‐Aminopyridines via Cobalt‐Catalyzed Cycloaddition of Diynes with N‐Substituted and N‐Unsubstituted Cyanamides;Advanced Synthesis & Catalysis;2023-10-02

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