Novel imidazo[2,1-b]thiazoles and imidazo[1,2-a]pyridines tethered with indolinone motif as VEGFR-2 inhibitors and apoptotic inducers: Design, synthesis and biological evaluations

Author:

Elkotamy Mahmoud S.,Elgohary Mohamed K.,Al-Rashood Sara T.,Almahli Hadia,Eldehna Wagdy M.,Abdel-Aziz Hatem A.

Funder

King Saud University

Publisher

Elsevier BV

Reference51 articles.

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4. J.M. Wood, G. Bold, E. Buchdunger, R. Cozens, S. Ferrari, J.r. Frei, F. Hofmann, J.r. Mestan, H. Mett, T. O'Reilly, PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration, Cancer research 60(8) (2000) 2178-2189.

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