Direct Demonstration That Loop1 of Scap Binds to Loop7-Reference-Cited by-同舟云学术

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Direct Demonstration That Loop1 of Scap Binds to Loop7

Published:2016-06 Issue:24 Volume:291 Page:12888-12896
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Zhang Yinxin,Lee Kwang Min,Kinch Lisa N.,Clark Lindsay,Grishin Nick V.,Rosenbaum Daniel M.,Brown Michael S.,Goldstein Joseph L.,Radhakrishnan Arun

Funder

National Institutes of Health

Welch Foundation

American Heart Association

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference16 articles.

1. Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL;Brown;J. Lipid Res,2009

2. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor;Brown;Cell,1997

3. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver;Horton;J. Clin. Invest,2002

4. Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance;Radhakrishnan;Cell Metab,2008

5. Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro;Sun;J. Biol. Chem,2005

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. DGAT2 inhibition blocks SREBP-1 cleavage and improves hepatic steatosis by increasing phosphatidylethanolamine in the ER;Cell Metabolism;2024-03

2. A cholesterol-binding bacterial toxin provides a strategy for identifying a specific Scap inhibitor that blocks lipid synthesis in animal cells;Proceedings of the National Academy of Sciences;2024-02-08

3. The role of cholesterol binding in the control of cholesterol by the Scap–Insig system;European Biophysics Journal;2022-06-19

4. Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensing;Cell;2021-07

5. Structural basis for sterol sensing by Scap and Insig;2021-06-03

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