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DGAT2 inhibition blocks SREBP-1 cleavage and improves hepatic steatosis by increasing phosphatidylethanolamine in the ER

  • Published:2024-03 Issue:3 Volume:36 Page:617-629.e7
  • ISSN:1550-4131
  • Container-title:Cell Metabolism
  • language:en
  • Short-container-title:Cell Metabolism

Author:

Rong Shunxing,Xia Mingfeng,Vale Goncalo,Wang Simeng,Kim Chai-Wan,Li Shili,McDonald Jeffrey G.,Radhakrishnan Arun,Horton Jay D.

Funder

Leducq Foundation

Welch Foundation

Science and Technology Commission of Shanghai Municipality

Merck

Pfizer

NIH

Publisher

Elsevier BV

Reference77 articles.

1. A multi-society Delphi consensus statement on new fatty liver disease nomenclature;Rinella;Hepatology,2023

2. Nonalcoholic fatty liver disease;Angulo;N. Engl. J. Med.,2002

3. Molecular mediators of hepatic steatosis and liver injury;Browning;J. Clin. Invest.,2004

4. Population-based risk factors and resource utilization for HCC: US perspective;Sanyal;Curr. Med. Res. Opin.,2010

5. Global Perspectives on Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis;Younossi;Hepatology,2018

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