The Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Active Site and Cleavage Sequence Differentially Regulate Protein Secretion from Proteolysis-Reference-Cited by-同舟云学术

The Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Active Site and Cleavage Sequence Differentially Regulate Protein Secretion from Proteolysis

Published:2014-10 Issue:42 Volume:289 Page:29030-29043
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Chorba John S.,Shokat Kevan M.

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference43 articles.

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2. Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype;Maxwell;Proc. Natl. Acad. Sci. U.S.A,2004

3. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia;Abifadel;Nat. Genet,2003

4. Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9;Cohen;Nat. Genet,2005

5. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease;Cohen;N. Engl. J. Med,2006

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