A Loss of Function Mutant of the Presenilin Homologue SEL-12 Undergoes Aberrant Endoproteolysis in Caenorhabditis elegans and Increases Aβ42 Generation in Human Cells-Reference-Cited by-同舟云学术

A Loss of Function Mutant of the Presenilin Homologue SEL-12 Undergoes Aberrant Endoproteolysis in Caenorhabditis elegans and Increases Aβ42 Generation in Human Cells

Published:2000-12 Issue:52 Volume:275 Page:40925-40932
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Okochi Masayasu,Eimer Stefan,Böttcher Andreas,Baumeister Ralf,Romig Helmut,Walter Jochen,Capell Anja,Steiner Harald,Haass Christian

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference77 articles.

1. Cellular processing of β-amyloid precursor protein and the genesis of amyloid β-peptide

2. β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

3. Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

4. Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity

5. Purification and cloning of amyloid precursor protein β-secretase from human brain

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