Activation of PPARα enhances astroglial uptake and degradation of β-amyloid
Author:
Affiliation:
1. Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.
2. Division of Research and Development, Jesse Brown Veterans Affairs Medical Center, Chicago, IL 60612, USA.
Abstract
Publisher
American Association for the Advancement of Science (AAAS)
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference60 articles.
1. Co-occurrence of Alzheimer's disease β-amyloid and tau pathologies at synapses
2. The role of intracellular amyloid β in Alzheimer's disease
3. Generation of amyloid β protein from its precursor is sequence specific
4. A Loss of Function Mutant of the Presenilin Homologue SEL-12 Undergoes Aberrant Endoproteolysis in Caenorhabditis elegans and Increases Aβ42 Generation in Human Cells
5. Maturation and Pro-peptide Cleavage of β-Secretase
Cited by 40 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Unveiling the role of astrogliosis in Alzheimer’s disease Pathology: Insights into mechanisms and therapeutic approaches;International Immunopharmacology;2024-11
2. Astrocytes and Memory: Implications for the Treatment of Memory-related Disorders;Current Neuropharmacology;2024-11
3. PPARs (Peroxisome Proliferator-activated Receptors) and Their Agonists in Alzheimer's Disease;Medicinal Chemistry;2024-10
4. Identification of Cinnamein, a Component of Balsam of Tolu/Peru, as a New Ligand of PPARα for Plaque Reduction and Memory Protection in a Mouse Model of Alzheimer’s Disease;Journal of Alzheimer's Disease Reports;2024-05-24
5. Propane-2-sulfonic acid octadec-9-enyl-amide, a novel PPARα/γ dual agonist, attenuates molecular pathological alterations in learning memory in AD mice;Neurological Research;2024-04-05
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3