Binding of a physiological substrate causes large-scale conformational reorganization in cytochrome P450 51-Reference-Cited by-同舟云学术

Binding of a physiological substrate causes large-scale conformational reorganization in cytochrome P450 51

Published:2018-12 Issue:50 Volume:293 Page:19344-19353
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Hargrove Tatiana Y.,Wawrzak Zdzislaw,Fisher Paxtyn M.,Child Stella A.^ORCID,Nes W. David,Guengerich F. Peter^ORCID,Waterman Michael R.,Lepesheva Galina I.^ORCID

Funder

HHS | National Institutes of Health (NIH)

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference37 articles.

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2. Mechanisms of cytochrome P450 substrate oxidation: MiniReview;Guengerich;J. Biochem. Mol. Toxicol,2007

3. Structural complex of sterol 14α-demethylase (CYP51) with 14α-methylenecyclopropyl-Δ7–24,25-dihydrolanosterol;Hargrove;J. Lipid Res,2012

4. Cytochrome P450 compound I: capture, characterization, and C–H bond activation kinetics;Rittle;Science,2010

5. CYP51 as drug targets for fungi and protozoan parasites: past, present and future;Lepesheva;Parasitology,2018

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