Oxidative decarboxylation of pyruvate by 1-deoxy-d-xyulose 5-phosphate synthase, a central metabolic enzyme in bacteria-Reference-Cited by-同舟云学术

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Oxidative decarboxylation of pyruvate by 1-deoxy-d-xyulose 5-phosphate synthase, a central metabolic enzyme in bacteria

Published:2018-07 Issue:28 Volume:293 Page:10857-10869
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

DeColli Alicia A.,Nemeria Natalia S.,Majumdar Ananya,Gerfen Gary J.,Jordan Frank,Freel Meyers Caren L.

Funder

HHS National Institutes of Health (NIH)

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference36 articles.

1. Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets?;Du;Int. J. Biol. Sci,2011

2. Vitamin B6 biosynthesis: formation of pyridoxine 5′-phosphate from 4-(phosphohydroxy)-l-threonine and 1-deoxy-d-xylulose-5-phosphate by PdxA and PdxJ protein;Laber;FEBS Lett,1999

3. The MEP pathway: a new target for the development of herbicides, antibiotics and antimalarial drugs;Rodríguez-Concepción;Curr. Pharm. Des,2004

4. Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-d-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol;Sprenger;Proc. Natl. Acad. Sci. U.S.A,1997

5. Hydroxybenzaldoximes are d-GAP-competitive inhibitors of E. coli 1-deoxy-d-xylulose-5-phosphate synthase;Bartee;Chembiochem,2015

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2. Potent Inhibition of E. coli DXP Synthase by a gem-Diaryl Bisubstrate Analog;ACS Infectious Diseases;2024-03-21

3. Disruption of an Active Site Network Leads to Activation of C2α-Lactylthiamin Diphosphate on the Antibacterial Target 1-Deoxy-d-xylulose-5-phosphate Synthase;Biochemistry;2024-02-23

4. Evaluation of ketoclomazone and its analogues as inhibitors of 1-deoxy-d-xylulose 5-phosphate synthases and other thiamine diphosphate (ThDP)-dependent enzymes;RSC Medicinal Chemistry;2024

5. Design of thiamine analogues for inhibition of thiamine diphosphate (ThDP)-dependent enzymes: Systematic investigation through Scaffold-Hopping and C2-Functionalisation;Bioorganic Chemistry;2023-09

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