Conformational Activation of Antithrombin by Heparin Involves an Altered Exosite Interaction with Protease-Reference-Cited by-同舟云学术

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Conformational Activation of Antithrombin by Heparin Involves an Altered Exosite Interaction with Protease

Published:2014-12 Issue:49 Volume:289 Page:34049-34064
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Izaguirre Gonzalo,Aguila Sonia,Qi Lixin,Swanson Richard,Roth Ryan,Rezaie Alireza R.,Gettins Peter G.W.,Olson Steven T.

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference37 articles.

1. Molecular mechanisms of antithrombin-heparin regulation of blood clotting proteinases: a paradigm for understanding proteinase regulation by serpin family protein proteinase inhibitors;Olson;Biochimie,2010

2. Antithrombin and its inherited deficiency states;van Boven;Semin. Hematol,1997

3. Complete antithrombin deficiency in mice results in embryonic lethality;Ishiguro;J. Clin. Invest,2000

4. Targeted mutagenesis of zebrafish antithrombin III triggers disseminated intravascular coagulation and thrombosis, revealing insight into function;Liu;Blood,2014

5. Cloned bovine aortic endothelial cells synthesize anticoagulantly active heparin sulfate proteoglycan;Marcum;J. Biol. Chem,1986

Cited by 28 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Acquired antithrombin deficiency in adult patients with postcardiotomy extracorporeal membrane oxygenation;Perfusion;2024-08-29

2. Molecular Mechanisms of the Impaired Heparin Pentasaccharide Interactions in 10 Antithrombin Heparin Binding Site Mutants Revealed by Enhanced Sampling Molecular Dynamics;Biomolecules;2024-06-04

3. A common protein C inhibitor exosite partially controls the heparin induced activation and inhibition of serine proteases;International Journal of Biological Macromolecules;2024-05

4. Interactions of proteins with heparan sulfate;Essays in Biochemistry;2024-04-22

5. The Interaction of Factor Xa and IXa with Non-Activated Antithrombin in Michaelis Complex: Insights from Enhanced-Sampling Molecular Dynamics Simulations;Biomolecules;2023-05-06

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