Cytochrome b5 shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy-Reference-Cited by-同舟云学术

Cytochrome b5 shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy

Published:2011-09 Issue:6 Volume:82 Page:669-680
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Kotrbová Věra,Mrázová Barbora,Moserová Michaela,Martínek Václav,Hodek Petr,Hudeček Jiří,Frei Eva,Stiborová Marie

Funder

Grant Agency of the Czech Republic

Ministry of Education of the Czech Republic

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference68 articles.

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2. Molecular mechanism of antineoplastic action of an anticancer drug ellipticine;Stiborová;Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub,2006

3. Cytochrome P450- and peroxidase-mediated oxidation of anticancer alkaloid ellipticine dictates its anti-tumor efficiency;Stiborová;Biochim Biophys Acta,2011

4. Multimodal action of antitumor agents on DNA: the ellipticine series;Auclair;Arch Biochem Biophys,1987

5. Extenting nature's leads: the anticancer agent ellipticine;Garbett;Curr Med Chem Anti-Cancer Agents,2004

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