Formation of potentially toxic metabolites of drugs in reactions catalyzed by human drug-metabolizing enzymes
Author:
Funder
Foundation for the National Institutes of Health
Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s00204-024-03710-9.pdf
Reference285 articles.
1. Abbasi A, Joswig-Jones CA, Jones JP (2020) Site-directed mutagenesis at the MoCo site of the human aldehyde oxidase: interrogating the kinetic differences between human and cynomolgus monkey. Drug Metab Dispos 48:1364–1371. https://doi.org/10.1124/dmd.120.000187
2. Amano T, Fukami T, Ogiso T, Hirose D, Jones JP, Taniguchi T, Nakajima M (2018) Identification of enzymes responsible for dantrolene metabolism in the human liver: A clue to uncover the cause of liver injury. Biochem Pharmacol 151:69–78. https://doi.org/10.1016/j.bcp.2018.03.002
3. Apak TI, Duffel MW (2004) Interactions of the stereoisomers of a-hydroxytamoxifen with human hydroxysteroid sulfotransferase SULT2A1 and rat hydroxysteroid sulfotransferase STa. Drug Metab Dispos 32:1501–1508. https://doi.org/10.1124/dmd.104.000919
4. Avent KM, DeVoss JJ, Gillam EMJ (2006) Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolites. Chem Res Toxicol 19:914–920. https://doi.org/10.1021/tx0600090
5. Baer BR, Wienkers LC, Rock DA (2007) Time-dependent inactivation of P450 3A4e by raloxifene; identification of Cys239 as the site of apoprotein alkylation. Chem Res Toxycol 20:954–964. https://doi.org/10.1021/tx7000337e
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