The anticancer agent ellipticine on activation by cytochrome P450 forms covalent DNA adducts☆1☆Supported by German Cancer Research Center, Grant Agency of the Czech Republic (grant 203/01/0996) and the Ministry of Education of the Czech Republic (grant MSM 1131 00001).1Abbreviations: α-NF, α-naphthoflavone; 3-IPMDIA, 3-isopropenyl-3-methyldiamantane; CHAPS, 3-[(3-cholamidopropyl)-dimethylammonio]-1-propane sulfonate; CYP, cytochrome P450; IC50, 50% inhibitory dose; MDR, multidrug resistance; PEI, polyethylenimine; RAL, relative adduct labeling; TLC, thin-layer chromatography-Reference-Cited by-同舟云学术

The anticancer agent ellipticine on activation by cytochrome P450 forms covalent DNA adducts☆1☆Supported by German Cancer Research Center, Grant Agency of the Czech Republic (grant 203/01/0996) and the Ministry of Education of the Czech Republic (grant MSM 1131 00001).1Abbreviations: α-NF, α-naphthoflavone; 3-IPMDIA, 3-isopropenyl-3-methyldiamantane; CHAPS, 3-[(3-cholamidopropyl)-dimethylammonio]-1-propane sulfonate; CYP, cytochrome P450; IC50, 50% inhibitory dose; MDR, multidrug resistance; PEI, polyethylenimine; RAL, relative adduct labeling; TLC, thin-layer chromatography

Published:2001-12 Issue:12 Volume:62 Page:1675-1684
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Stiborová Marie,Bieler Christian A.,Wiessler Manfred,Frei Eva

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

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