Wild bitter gourd extract up-regulates mRNA expression of PPARα, PPARγ and their target genes in C57BL/6J mice

Author:

Chao Che-Yi,Yin Mei-Chin,Huang Ching-jang

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference24 articles.

1. Transcriptional and post-transcriptional analysis of peroxisomal protein encoding genes from rat treated with an hypolipidemic agent, ciprofibrate. Effect of an intermittent treatment and influence of obesity;Caira;Biochemical Pharmacology,1995

2. Ragaglitazar: a novel PPARα & PPARγ agonist with potent lipid-lowering and insulin-sensitizing efficacy in animal models;Chakrabarti;British Journal of Clinical Pharmacology,2003

3. Bitter gourd (Momordica charantia) extract activates peroxisome proliferator-activated receptors and up-regulates the expression of the acyl-CoA oxidase gene in H4IIEC3 hepatoma cells;Chao;Journal of Biomedical Science,2003

4. Oxidized frying oil up-regulated hepatic acyl-CoA oxidase and cytochrome P450 4A1 genes in rats and activates PPARα;Chao;The Journal of Nutrition,2001

5. Fractionation and identification of 9c, 11t, 13t-conjugated linolenic acid as an activator of PPARα in bitter gourd (Momordica charantia L.);Chuang;Journal of Biomedical Science,2006

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