Ganoderiol F, a ganoderma triterpene, induces senescence in hepatoma HepG2 cells

Author:

Chang Ue-Min,Li Chyi-Hann,Lin Liang-In,Huang Cheng-Po,Kan Lou-Sing,Lin Shwu-Bin

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference27 articles.

1. Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts;Alcorta;Proceedings of the National Academy of Sciences of the United States of America,1996

2. Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme;Burden;Biochimica et Biophysica Acta,1998

3. Pak4 induces premature senescence via a pathway requiring p16INK4/p19ARF and mitogen-activated protein kinase signaling;Cammarano;Molecular and Cellular Biology,2005

4. Suppressing cancer: the importance of being senescent;Campisi;Science,2005

5. A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents;Chang;Cancer Research,1999

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