Quantitative low-dose assessment of seafood toxin, domoic acid, in the rat brain: application of physiologically-based pharmacokinetic (PBPK) modeling

Author:

Kim Chung S,Ross Ivan A,Sandberg Jennifer A,Preston Edward

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,General Medicine

Reference23 articles.

1. Arms, A.D., Travis, C.C., 1988. Reference Physiological Parameters in Pharmacokinetic Modeling. Office of Health and Environmental Assessment. US Environmental Protection Agency, Washington, DC, NTIS PB88-196019.

2. Collins, R.C., 1987. Neurotoxins and the selective vulnerability of brain. In: P. Jenner (Ed.), Neurotoxins and Their Pharmacological Implications, Raven Press, New York, p. 1.

3. Distribution of cardiac output during diurnal changes of activity in rats;Delp;Am. J. Physiol.,1991

4. Domoic acid poisoning and mussel-associated intoxication: Preliminary investigations into the response of mice and rats to toxic mussel extract;Iverson;Food Chem. Toxicol.,1989

5. Transport of 2,4,5-trichlorophenoxyacetic acid across the blood-cerebrospinal fluid barrier of the rabbit;Kim;J. Pharmacol. Exp. Ther.,1993

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