Base-modified oligodeoxynucleotides. I. effect of 5-alkyl, 5-(1-alkenyl) and 5-(1-alkynyl) substitution of the pyrimidines on duplex stability and hydrophobicity
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference22 articles.
1. Antisense oligonucleotides: a new therapeutic principle
2. Antisense oligodeoxynucleotides as antiviral agents
3. Synthesis of Base Modified Phosphorothioate Oligodeoxynucleotides as Inhibitors of HIV-1
4. Incorporation of a complete set of deoxyadenosine and thymidine analogs suitable for the study of protein nucleic acid interactions into oligodeoxynucleotides. Application to the EcoRV restriction endonuclease and modification methylase
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