Synthesis of Base Modified Phosphorothioate Oligodeoxynucleotides as Inhibitors of HIV-1
Author:
Affiliation:
1. a Department of Chemistry , West Mains Road, Edinburgh , EH9 3JJ , Scotland , U.K.
2. b Institute of Genetics, University of Edinburgh , West Mains Road, Edinburgh , EH9 3JJ , Scotland , U.K.
Publisher
Informa UK Limited
Subject
Genetics,Biochemistry
Link
https://www.tandfonline.com/doi/pdf/10.1080/07328319108046526
Reference14 articles.
1. Inhibition of human immunodeficiency virus replication by antisense oligodeoxynucleotides.
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4. Oligodeoxynucleotides
5. Phosphorothioate analogs of oligodeoxynucleotides: inhibitors of replication and cytopathic effects of human immunodeficiency virus.
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1. O-Selectivity and Utility of Phosphorylation Mediated by Phosphite Triester Intermediates in the N-Unprotected Phosphoramidite Method;Journal of the American Chemical Society;2004-08-17
2. Preparation and Properties of Oligodeoxynucleotides Containing 5-Iodouracil and 5-Bromo- and 5-Iodocytosine;Bioconjugate Chemistry;1997-09-01
3. Design, Biological Properties and Delivery of Antisense Oligonucleotides;Targeting of Drugs 4;1994
4. Gene-Mimetic Substances: Drugs Designed to Intervene in Gene Expression;Advances in Pharmacology;1994
5. Base-modified oligodeoxynucleotides. I. effect of 5-alkyl, 5-(1-alkenyl) and 5-(1-alkynyl) substitution of the pyrimidines on duplex stability and hydrophobicity;Tetrahedron Letters;1993-03
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