Protective effects of acarbose against vascular endothelial dysfunction through inhibiting Nox4/NLRP3 inflammasome pathway in diabetic rats

Author:

Li Xiao-Xue,Ling Sun-Kai,Hu Ming-Yue,Ma Yu,Li Yuan,Huang Pei-Lin

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Physiology (medical),Biochemistry

Reference54 articles.

1. Glucose-lowering treatment in cardiovascular and peripheral artery disease;Suades;Curr. Opin. Pharmacol.,2018

2. Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial;Chiasson;Jama,2003

3. Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial, the lancet;Holman;Diabetes Endocrinol.,2017

4. Pleiotropic effects of acarbose on atherosclerosis development in rabbits are mediated via upregulating AMPK signals;Chan;Sci. Rep.,2016

5. Acarbose inhibits the proliferation and migration of vascular smooth muscle cells via targeting Ras signaling;Yu;Vasc. Pharmacol.,2018

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