Review on the role of nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome pathway in diabetes: mechanistic insights and therapeutic implications

Author:

Satheesan AbhishekORCID,Kumar JanardananORCID,Leela Kakithakara Vajravelu,Murugesan Ria,Chaithanya Venkata,Angelin Matcha

Publisher

Springer Science and Business Media LLC

Reference182 articles.

1. Alzokaky AA et al (2023) Metformin ameliorates doxorubicin-induced cardiotoxicity targeting HMGB1/TLR4/NLRP3 signaling pathway in mice. Life Sci 316:121390

2. Amaral NB et al (2023) Colchicine reduces the activation of NLRP3 inflammasome in COVID-19 patients. Inflamm Res off J Eur Histamine Res Soc 72(5):895–899

3. Amin FM, Shehatou GSG, Nader MA, Abdelaziz RR (2023) Piperine mitigates aortic vasculopathy in streptozotocin-diabetic rats via targeting TXNIP-NLRP3 signaling. Life Sci 314:121275

4. Arab HH, Ashour AM, Gad AM, Mahmoud AM, Kabel AM (2021) Activation of AMPK/mTOR-driven autophagy and inhibition of NLRP3 inflammasome by saxagliptin ameliorate ethanol-induced gastric mucosal damage. Life Sci 280:119743

5. Awad AM, Elshaer SL, Gangaraju R, Abdelaziz RR, Nader MA (2024) Ameliorative effect of montelukast against STZ induced diabetic nephropathy: targeting HMGB1, TLR4, NF-κB, NLRP3 inflammasome, and autophagy pathways. Inflammopharmacology 32(1):495–508

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