Use of a systems model of drug-induced liver injury (DILIsym®) to elucidate the mechanistic differences between acetaminophen and its less-toxic isomer, AMAP, in mice
Author:
Publisher
Elsevier BV
Subject
Toxicology,General Medicine
Reference56 articles.
1. Can in vitro metabolism-dependent covalent binding data distinguish hepatotoxic from nonhepatotoxic drugs? An analysis using human hepatocytes and liver S-9 fraction;Bauman;Chem. Res. Toxicol.,2009
2. Modeling drug- and chemical-induced hepatotoxicity with systems biology approaches;Bhattacharya;Front. Physiol.,2012
3. Selective protein arylation by acetaminophen and 2,6-dimethylacetaminophen in cultured hepatocytes from phenobarbital-induced and uninduced mice. Relationship to cytotoxicity;Birge;Biochem. Pharmacol.,1989
4. Drug-induced liver injury: review article;Bleibel;Dig. Dis. Sci.,2007
5. Physiological parameter values for physiologically based pharmacokinetic models;Brown;Toxicol. Ind. Health,1997
Cited by 32 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for Macromolecules, Provides Mechanistic Understanding of Tocilizumab- and GGF2-Induced Liver Injury;International Journal of Molecular Sciences;2023-06-02
2. Treatment of chronic hepatitis D with peginterferon lambda—the phase 2 LIMT-1 clinical trial;Hepatology;2023-02-20
3. Investigating bile acid-mediated cholestatic drug-induced liver injury using a mechanistic model of multidrug resistance protein 3 (MDR3) inhibition;Frontiers in Pharmacology;2023-01-17
4. Unraveling the effect of intra- and intercellular processes on acetaminophen-induced liver injury;npj Systems Biology and Applications;2022-08-06
5. Preclinical models of idiosyncratic drug-induced liver injury (iDILI): Moving towards prediction;Acta Pharmaceutica Sinica B;2021-12
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3