Case studies to test: A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments

Author:

Blackburn Karen,Bjerke Donald,Daston George,Felter Susan,Mahony Catherine,Naciff Jorge,Robison Steven,Wu Shengde

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference109 articles.

1. Albemarle Corp, 2008. (posting date). EPA-HQ-OPPT-2005-0033-0181, Test Rule Requirements: AN 702 (CAS 118-82-1). http://www.regulations.gov/search/Regs/home.html#documentDetail?R=09000064801af23a.

2. Albemarle Corp, 2007. EPA-HQ-OPPT-2005-0033-0250. http://www.regulations.gov/search/Regs/home.html#documentDetail?R=0900006480254793.

3. American Chemistry Council Benzene, Toluene, and Xylenes VCCEP Consortium. (2005). Xylenes Category: m-Xylene (CAS No. 108-38-3), o-Xylene (CAS No. 95-47-6), p-Xylene (CAS No. 106-42-3), Mixed Xylenes (CAS No. 1330-20-7) Voluntary Children’s Chemical Evaluation Program (VCCEP) Tier 1 Pilot Submission Docket Number OPPTS – 00274D.

4. The American Chemistry Council, Rubber and Plastic Additives Panel of July 2003. Bridged Alkyl phenols Category Justification and Testing Rationale.

5. Arcadis, 2006. Robust Summaries and Test Plan for 1,2-dimethyl-4-nitrobenzene (CAS No. 99-51-4).

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