Identifying chemicals based on receptor binding/bioactivation/mechanistic explanation associated with potential to elicit hepatotoxicity and to support structure activity relationship-based read-across

Author:

Wu Shengde,Daston George,Rose Jane,Blackburn Karen,Fisher Joan,Reis Allison,Selman Bastian,Naciff Jorge

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Toxicology,Applied Microbiology and Biotechnology

Reference139 articles.

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2. A comparative 90-day toxicity study of allyl acetate, allyl alcohol and acrolein;Auerbach;Toxicology,2008

3. Becker, K. L. (2001) Principles and Practice of Endocrinology and Metabolism, Ed by Becker, K. L. Lippincott Williams & Wilkins, 2001- Medical-2477 pages.

4. PPAR-gamma agonists and their effects on IGF-I receptor signaling: Implications for cancer;Belfiore;PPAR Res.,2009

5. The hepatotoxicity of rhein involves impairment of mitochondrial functions;Bironait;Chemico-Biological Interactions,1997

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