Developing and validating read-across workflows that enable decision making for toxicity and potency: Case studies with N-nitrosamines

Author:

Kane Steven,Newman Dan,Ponting David J.,Rosser Edward,Thomas Robert,Vessey Jonathan D.ORCID,Webb Samuel J.,Wood William H.J.

Publisher

Elsevier BV

Reference84 articles.

1. European Chemicals Agency, Read-Across Assessment Framework (RAAF), (n.d.). https://echa.europa.eu/documents/10162/13628/raaf_en.pdf/614e5d61-891d-4154-8a47-87efebd1851a (accessed August 23, 2022).

2. A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments;Wu;Regul. Toxicol. Pharm.,2010

3. Toward Good Read-Across Practice (GRAP) guidance;Ball;ALTEX – Altern. Anim. Exper.,2016

4. Read-across methodology in toxicological risk assessment;Escher;Regul. Toxicol.,2021

5. Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information;Shah;Regul. Toxicol. Pharm.,2016

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