How sensitive does chemical characterization of medical devices need to be? Calibration of analytical evaluation thresholds with the carcinogenic potency database

Author:

Kennedy Todd A.ORCID,Spinti Mark J.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference27 articles.

1. Origin of the TTC values for compounds that are genotoxic and/or carcinogenic and an approach for their re-evaluation;Boobis;Crit. Rev. Toxicol.,2017

2. Risk assessment of peak exposure to genotoxic carcinogens: a pragmatic approach;Bos;Toxicol. Lett.,2004

3. Estimation of toxic hazard-a decision tree approach;Cramer;Food Chem. Toxicol.,1978

4. Opinion of the scientific committee on a request from EFSA related to a harmonised approach for risk assessment of substances which are both genotoxic and carcinogenic;EFSA Journal,2005

5. Scientific opinion on exploring options for providing advice about possible human health risks based on the concept of Threshold of Toxicological Concern (TTC);EFSA Journal,2012

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