Investigation of the stabilisation of freeze-dried lysozyme and the physical properties of the formulations

Author:

Liao Yong-Hong,Brown Marc B,Martin Gary P

Publisher

Elsevier BV

Subject

Pharmaceutical Science,General Medicine,Biotechnology

Reference30 articles.

1. The stability of insulin in the crystalline and amorphous solid: observation of greater stability for amorphous form;Pikal;Pharm. Res.,1997

2. Phase separation of excipients during lyophilization: effects on protein stability;Randolph;J. Pharm. Sci.,1997

3. The role of vitrification in anhydrobiosis;Crowe;Ann. Rev. Physiol.,1998

4. Physical factors affecting the storage stability of freeze-dried Interleukin-1 receptor antagonist: glass transition and protein conformation;Chang;Arch. Biochem. Biophys.,1996

5. Freezing and drying-induced perturbations of protein structure and mechanisms of protein protection by stabilizing additives;Carpenter,1999

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