Molecular engineering strategies and methods for the expression and purification of IgG1-based bispecific bivalent antibodies
Author:
Publisher
Elsevier BV
Subject
General Biochemistry, Genetics and Molecular Biology,Molecular Biology
Reference37 articles.
1. The Design and Characterization of Oligospecific Antibodies for Simultaneous Targeting of Multiple Disease Mediators
2. Insertion of scFv into the hinge domain of full-length IgG1 monoclonal antibody results in tetravalent bispecific molecule with robust properties
3. CD19 and CD32b Differentially Regulate Human B Cell Responsiveness
4. A multifunctional bispecific antibody protects against Pseudomonas aeruginosa
5. A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy
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1. Manufacturability and functionality assessment of different formats of T-cell engaging bispecific antibodies;mAbs;2023-07-04
2. Generation of robust bispecific antibodies through fusion of single-domain antibodies on IgG scaffolds: a comprehensive comparison of formats;mAbs;2023-03-20
3. Ceramic hydroxyapatite chromatography plays a critical role in bispecific antibody purification process for impurity removal;Antibody Therapeutics;2022-11-19
4. Role of harvest depth filtration in controlling product-related impurities for a bispecific antibody;Antibody Therapeutics;2022-09-26
5. Effective flow-through polishing strategies for knob-into-hole bispecific antibodies;Bioresources and Bioprocessing;2022-09-14
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